The ACTN3 R577X variant in sprint and strength performance

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چکیده

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The ACTN3 R577X variant in sprint and strength performance

PURPOSE The aim of this study is to examine the association between the distribution of ACTN3 genotypes and alleles in power, speed, and strength-oriented athletics. METHODS ACTN3 genotyping was carried out for a total of 975 Korean participants: top-level sprinters (n = 58), top-level strength athletes (n = 63), and healthy controls (n = 854). RESULTS Genetic associations were evaluated by...

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Is the interaction between HIF1A P582S and ACTN3 R577X determinant for power/sprint performance?

Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that regulates gene expression in response to hypoxia and has been associated with athletic performance. The aims of this study were (1) to determine the frequency distribution of HIF1A Pro582Ser (rs11549465) polymorphism among 155 Israeli athletes (sprinters and endurance athletes) and 240 healthy controls and (2) to analyze the infl...

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The ACTN3 R577X polymorphism in East and West African athletes.

PURPOSE To determine the frequency of the ACTN3 R577X polymorphism (functional R allele and nonfunctional X allele) in a variety of African populations and to examine its influence on the success of elite East African endurance runners and West African sprinters. METHODS The R577X polymorphism was genotyped in 198 Ethiopian controls and 76 elite Ethiopian endurance athletes, 158 Kenyan contro...

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ACTN3 R577X Polymorphism and Neuromuscular Response to Resistance Training.

The R577X polymorphism at the ACTN3 gene has been associated with muscle strength, hypertrophy and athletic status. The X allele, which is associated with the absence of ACTN3 protein is supposed to impair performance of high force/velocity muscle contractions. The purpose of the present study was to investigate the association of the R577X polymorphism with the muscle response to resistance tr...

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ACTN3 R577X genotype and performance of elite middle-long distance swimmers in China

The ACTN3 gene is one of the genes that have a potential influence on physical performance. Studies have shown that the 577R genotype of ACTN3 is more prevalent in sprint athletes, while the 577X genotype is more prevalent in endurance athletes. In swimming, both power and endurance related phenotypes are equally needed for swimmers to excel at the elite level. Therefore, the ACTN3 R577X polymo...

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ژورنال

عنوان ژورنال: Journal of Exercise Nutrition and Biochemistry

سال: 2014

ISSN: 2233-6834,2233-6842

DOI: 10.5717/jenb.2014.18.4.347